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KMID : 1123920090230030700
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Korean Journal of Oriental Physiology and Pathology
2009 Volume.23 No. 3 p.700 ~ p.703
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Anti-hypertensive Effects of Electroacupuncture at ST36 In Spontaneously Hypertensive Rat
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Park Hyun-Jung
Kim Hee-Young
Kim Sung-Ok
Hahm Dae-Hyun
Lee Hye-Jung
Shim In-Sop
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Abstract
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The present study investigated whether electroacupuncture (EA) can alleviate hypertension and concomitant disorders such as decreased kidney weight and elevation of serum creatinine in spontaneous hypertensive rats. EA (2 Hz, 3 mA, 10 min) was applied to Joksamni (ST36) once daily for 7 days. Body weight, blood pressure and heart rate were measured on Day 0, 2, 6, 8, 10 and 12, and kidney weight and serum creatinine levels were examined after sacrifice (on Day 12 after last examination). In the ST36 group, the blood pressure were significantly decreased from 6thdays and its effects lasted up to Day12 (up to 5days after cessation of acupuncture), compared to control. And, significant decreases of the heart rates after EA at ST36 were also observed on Day 2, 6, and 8. However, there were no significant differences in daily body weight, kidney weight and serum creatinine between acupuncture and control group. These results showed that EA at ST36 caused anti-hypertension by decreasing blood pressure and heart rates in spontaneous hypertenstive rats, although it failed to alleviate concomitant disorders such as the decreased kidney weight and elevation of serum creatinine shown in hypertensive rats.
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KEYWORD
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Joksamni (ST36), spontaneously hypertensive rat, electroacupuncture
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